GAG= glycosaminogylcans
Reseach Studies
More research

Glucosamine HCL:
In addition to being the main substrate for the biosynthesis of glycosaminoglycans and hyaluronic acid, the primary function of glucosamine is to stimulate the secretion of glycosaminoglycans in the articular cartilage.  It was also found to provide natural protection against the cartilage-damaging effects of some NSAIDs.

Chondroitin:
In addition to being the major glycosaminogylcans found in cartilage, its primary function is to inhibit degradative enzymes. Degradative enzymes contribute to cartilage breakdown.

Physician's Desk Reference, 1999.
 

>From The Pill Book For Pets, 1998:
Oral glycosaminoglycans are derived from a number of natural sources. Cartilage from cattle or sharks is the most common source.

There is extensive anecdotal and clinical evidence that oral GAGs may be useful, but the well-controlled studies needed to confirm these observations are lacking.

Cautions And Warnings:
Do not use in place of accurate diagnosis, professional treatment, or in infected joints.

Possible Side Effects:  rare: diarrhea

Puppies/kittens:  There are no well-controlled studies in puppies and kittens.  Oversupplementation of nutrients, minerals and vitamins may increase the risk of developmental diseases in growing pups.  Use only if the benefits outweigh the risks.

Senior Animals:  Oral GAGs are probably safe, but there are also no well-controlled studies in seniors.  The major risk is that owners may use GAGs instead of seeking veterinary advice and could delay accurate diagnosis and treatment of serious problems.
 
 

Sandy Suarez Boutin Great Dane Rescue, Inc
 
 

What is Glucosamine ?

                         Glucosamine is a natural substance found in the human body. It plays an important role in the health
                         and resiliency of your cartilage. Cartilage is the soft tissue that forms the cushions that keep your
                         bones from grinding against each other in your joints. Without cartilage, your knees and elbows would
                         quickly wear out.

                         If people already have Glucosamine in their bodies, why do they need to take more ?

                         As we age, we lose some of the glucosamine and other substances in our cartilage. This can lead to
                         the thinning of our cartilage and to the onset and progression of osteoarthritis, the most common type of
                         arthritis.
 
 

                 Glucosamine has also been hailed as a remedy for the relief of osteoarthritis symptoms.
                 It may improve symptoms in selected patients with osteoarthritis, according to
                 preliminary European studies, but definitive longterm proof is lacking. Glucosamine has
                 not been evaluated for other forms of arthritis.
 

                         What is Chondroitin ?

                         Chondroitin is made from two sugar like molecules that are attached to each other. Long chains of
                         chondroitins form part of the ground substance of cartilage tissue and help to make cartilage resilient to
                         the pressures it experiences from bearing weight.

                         How do I know I am getting the right formula ?

                         Research of over 300 clinical studies have shown that the proper combination ratio of 5:4 of
                         Glucosamine & Chondroitin, which is found in our formula, enable the formation of spongy shock
                         absorber within cartilage which decreases the chances of the cartilage becoming malnutritioned, dried,
                         thinned, and therefore more susceptible to deterioration and injury.

                         Benefits :

                         Research shows this formula supports and nourishes :

                         - All Joints, Hands, Wrists, Knees, Neck, Back, Hips, Ankles, and Feet

                         - Cartilage tissue throughout the body

                         - Aids in preventing and treating Osteoarthritis, Arthritis, Bone injuries, Joint injuries and more...

                         - Great for athletes to maintain healthy, strong bones and maintain stamina!